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Profhilo is an ultra pure hyaluronic acid based bio-remodelling procedure which is produced without the addition of cross-linked chemical materials. It features a nanotechnological structure and it is implemented to a few specific points. Stabilized and injectable hyaluronic acid based product doesn’t include BDDE and it is developed uniquely to tighten the tissues and enhance skin elasticity on the areas where aging starts to show its signs first, such as the face hands, neck and arms.

Profhilo isn’t an ordinary filler or a bio-revitalizing solution. It is rather a new generation skin rejuvenation procedure. It is manufactured by Nahyco Hybrid Technology and it doesn’t include any chemicals. Unlike traditional fillers which are used to provide volume, FDA and CE approved Profhilo softens up the fine wrinkles and lines, tightens the skin, balances the skin tone by stimulating 4 types of collagens on each layer of the skin. Profhilo enrichens, moisturizes and revitalizes the skin, giving it a natural and youthful glow. It reconstructs the elastic fibers and collagen which start deteriorating with aging.

Profhilo stable hybrid complex is the first patented product which was developed by IBSA using a Nahyco Hybrid Technology. Profhilo includes 32 mg low molecular weight HA (at 80-100K) and 32 mg high molecular weight HA (1100-1400). Thermal cross-linking changes the structure and attributes of hyaluronic acid and forms new hybrid complexes that modulate the tissues. This is the explanation of different biological attributes between the H-HA and L-HA.

One of its main advantages is that it lasts longer. Compared to standalone H-HA or L-HA which are frequently used in biorevitalisation products, natural hyaluronidase (BTH) digestion is slow. Compared to H-HA and L-HA, one of the advantages of consistent cooperative hybrid complex is the increase in type 1 and type 3 collagen and keratinocytes as well as the type 4 and type 7 collagen expression levels.


What are the objectives of Profhilo 5 Point Technique?

  • Shiny and fine skin texture
  • Tissue repair
  • Younger skin
  • Intensive moisturization and tightening.


What is Profhilo 5 Point Technique?

The procedure is implemented on 5 BAP points on the face. The procedure reaches each layer of the skin after being implemented on these 5 point: Epidermis, Dermis and Subcutaneous. These 5 areas do not pose any risks since they are quite far away from nerves and main blood vessels, which ensures maximum safety.

Profhilo 5 point technique could also be used on the neck, back of the hands, kneecaps, arms, upper chest besides the face.


BAP points:

What are the Main Differences of Profhilo Compared to Other Fillers?

Profhilo moisturizes the skin with the ‘Hydro’ effect thanks to L-HA.

Profhilo provides volume on the dermis thanks to H-HA.

It provides and sustains the most convenient conditions for Fibroblasts, keratinocytes and adipocytes to survive, by helping the extracellular matrix to reshape in terms of flexibility and support.

Hyaluroniv acid is slowly emitted from the hybrid complexes. That’s why it doesn’t trigger inflammatory cytokines and this minimizes the swelling and bruising risk, making it biocompatible. This increases patient comfort during and after the treatment.

Profhilo is a collagen stimulant unlike other fillers. Besides its filler effect, it eliminates wrinkles and signs of aging and rejuvenates the tissue where it’s applied.


Areas Suitable for Profhilo Procedure

Although Profhilo is generally applied on the face, it could also be used on other parts of the body such as:

  1. Neck
  2. Upper Chest Area
  3. Hands
  4. Arms
  5. Knee Caps.


Does the Patient Feel Pain During the Profhilo Procedure?

This procedure features an advanced technological infrastructure and a specially developed injection technique is used. Since the number of injection areas is low compared to traditional fillers, the patient doesn’t feel pain.


What are the Advantages of Profhilo 5 Points Technique?

  • Efficient results are achieved quickly.
  • The procedure doesn’t take long.
  • Filler and double tightening effect is achieved together.


Does Profhilo Cause Allergic Reactions?

Since the procedure doesn’t contain any chemicals, it doesn’t pose any allergy risks. Profhilo procedure is compliant with FDA and EU standards.